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Synthesis and Biological Activity of the Pinostrobin Oxime Complex Compounds with Some d-Metals

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dc.contributor.author A. A. Mashentseva
dc.contributor.author T. S. Seytembetov
dc.contributor.author S. M. Adekenov
dc.contributor.author B. I. Tuleuov
dc.contributor.author O. P. Loiko
dc.contributor.author A. I. Khalitova
dc.date.accessioned 2012-09-21T16:41:54Z
dc.date.available 2012-09-21T16:41:54Z
dc.date.issued 2012-09-21
dc.identifier.issn 1070-3632
dc.identifier.uri http://dspace.enu.kz/handle/data/2051
dc.description ISSN 1070-3632, Russian Journal of General Chemistry, 2011, Vol. 81, No. 1, pp. 96–101. © Pleiades Publishing, Ltd., 2011. en_US
dc.description.abstract The process of the complex formation by the natural flavonoid pinostrobin (5-hydroxy-7-methoxyflavonone) oxime with the Cu(II) and Fe(III) ions in a water–ethanol medium was investigated. The metal : ligand ratio in the complex was determined by the saturation method. The results of the analysis of IR spectra and the data of mass-pectrometric studies of the structure of the obtained complex compounds are reported. The antiviral activity of the synthesized complexes with respect to the human immunodeficiency virus HIV-1 IIIB and HIV-2 ROD strains was studied. The antioxidant activity of the complexes, as well as the parent pinostrobin oxime ligand, was evaluated with respect to the diphenylpicrylhydrazyl (DPPH) radical and the 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical cation. en_US
dc.language.iso en en_US
dc.title Synthesis and Biological Activity of the Pinostrobin Oxime Complex Compounds with Some d-Metals en_US


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